Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes.

The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches based on countin...

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Bibliographic Details
Main Authors: Mark Lipson, Po-Ru Loh, Sriram Sankararaman, Nick Patterson, Bonnie Berger, David Reich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4642934?pdf=render