Epistatic interaction between BANK1 and BLK in rheumatoid arthritis: results from a large trans-ethnic meta-analysis.

BACKGROUND: BANK1 and BLK belong to the pleiotropic autoimmune genes; recently, epistasis between BANK1 and BLK was detected in systemic lupus erythematosus. Although BLK has been reproducibly identified as a risk factor in rheumatoid arthritis (RA), reports are conflicting about the contribution of...

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Main Authors: Emmanuelle Génin, Baptiste Coustet, Yannick Allanore, Ikue Ito, Maria Teruel, Arnaud Constantin, Thierry Schaeverbeke, Adeline Ruyssen-Witrand, Shigeto Tohma, Alain Cantagrel, Olivier Vittecoq, Thomas Barnetche, Xavier Le Loët, Patrice Fardellone, Hiroshi Furukawa, Olivier Meyer, Benjamin Fernández-Gutiérrez, Alejandro Balsa, Miguel A González-Gay, Gilles Chiocchia, Naoyuki Tsuchiya, Javier Martin, Philippe Dieudé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639995?pdf=render