Mapping RNA–RNA interactome and RNA structure in vivo by MARIO

Current methods for mapping RNA-RNA interactions have to rely on an ‘anchor’ protein or RNA. Here, the authors report the MARIO (Mapping RNA interactome in vivo) technology that can massively reveal RNA-RNA interactions and RNA structure from unperturbed cells.

Bibliographic Details
Main Authors: Tri C. Nguyen, Xiaoyi Cao, Pengfei Yu, Shu Xiao, Jia Lu, Fernando H. Biase, Bharat Sridhar, Norman Huang, Kang Zhang, Sheng Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12023