Mapping RNA–RNA interactome and RNA structure in vivo by MARIO

Current methods for mapping RNA-RNA interactions have to rely on an ‘anchor’ protein or RNA. Here, the authors report the MARIO (Mapping RNA interactome in vivo) technology that can massively reveal RNA-RNA interactions and RNA structure from unperturbed cells.

Bibliographic Details
Main Authors: Tri C. Nguyen, Xiaoyi Cao, Pengfei Yu, Shu Xiao, Jia Lu, Fernando H. Biase, Bharat Sridhar, Norman Huang, Kang Zhang, Sheng Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12023
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spelling doaj-d5cca83795c342d68d39b49fcda76f392021-05-11T10:58:24ZengNature Publishing GroupNature Communications2041-17232016-06-017111210.1038/ncomms12023Mapping RNA–RNA interactome and RNA structure in vivo by MARIOTri C. Nguyen0Xiaoyi Cao1Pengfei Yu2Shu Xiao3Jia Lu4Fernando H. Biase5Bharat Sridhar6Norman Huang7Kang Zhang8Sheng Zhong9Department of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoDepartment of Ophthalmology, University of California, San DiegoDepartment of Bioengineering, University of California, San DiegoCurrent methods for mapping RNA-RNA interactions have to rely on an ‘anchor’ protein or RNA. Here, the authors report the MARIO (Mapping RNA interactome in vivo) technology that can massively reveal RNA-RNA interactions and RNA structure from unperturbed cells.https://doi.org/10.1038/ncomms12023
collection DOAJ
language English
format Article
sources DOAJ
author Tri C. Nguyen
Xiaoyi Cao
Pengfei Yu
Shu Xiao
Jia Lu
Fernando H. Biase
Bharat Sridhar
Norman Huang
Kang Zhang
Sheng Zhong
spellingShingle Tri C. Nguyen
Xiaoyi Cao
Pengfei Yu
Shu Xiao
Jia Lu
Fernando H. Biase
Bharat Sridhar
Norman Huang
Kang Zhang
Sheng Zhong
Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
Nature Communications
author_facet Tri C. Nguyen
Xiaoyi Cao
Pengfei Yu
Shu Xiao
Jia Lu
Fernando H. Biase
Bharat Sridhar
Norman Huang
Kang Zhang
Sheng Zhong
author_sort Tri C. Nguyen
title Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
title_short Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
title_full Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
title_fullStr Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
title_full_unstemmed Mapping RNA–RNA interactome and RNA structure in vivo by MARIO
title_sort mapping rna–rna interactome and rna structure in vivo by mario
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-06-01
description Current methods for mapping RNA-RNA interactions have to rely on an ‘anchor’ protein or RNA. Here, the authors report the MARIO (Mapping RNA interactome in vivo) technology that can massively reveal RNA-RNA interactions and RNA structure from unperturbed cells.
url https://doi.org/10.1038/ncomms12023
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