Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

Caspase 3 (CASP3) has a key role in the execution of apoptosis, and many cancer cells are believed to disable CASP3 as a mechanism of resistance to cytotoxic therapeutics. Alongside, CASP3 regulates stress-responsive immunomodulatory pathways, including secretion of type I interferon (IFN). Here, we...

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Bibliographic Details
Main Authors: Maria Esperanza Rodriguez-Ruiz, Aitziber Buqué, Michal Hensler, Jonathan Chen, Norma Bloy, Giulia Petroni, Ai Sato, Takahiro Yamazaki, Jitka Fucikova, Lorenzo Galluzzi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
agr3
apaf1
bcl2
casp9
stc2
sting
susd3
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1655964

Internet

http://dx.doi.org/10.1080/2162402X.2019.1655964

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