Stability of Recombinant Tissue Plasminogen Activator at −30 °C over One Year

Recombinant tissue plasminogen activator (rt-PA) is used to restore patency and avoid inadvertent removal of peripheral and central venous catheters. rt-PA was reconstituted (1 mg/mL) then cryopreserved at −30 °C for 1, 2, 3, 6, 8, and 12 months and, then its stability was...

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Bibliographic Details
Main Author: Abdulmalik Alkatheri
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/6/1/25