Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis

Type 1 diabetes (T1D) is a chronic immune-mediated disease resulting from the selective destruction of the insulin-producing pancreatic islet β-cells. Susceptibility to the disease is the result of complex interactions between environmental and genetic risk factors. Genome-wide association studies (...

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Bibliographic Details
Main Authors: Joachim Størling, Flemming Pociot
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/8/2/72