Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

Abstract Background DNA methylation alteration extensively associates with smoking and is a plausible link between smoking and adverse health. We examined the association between epigenome-wide DNA methylation and serum cotinine levels as a proxy of nicotine exposure and smoking quantity, assessed t...

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Bibliographic Details
Main Authors: Richa Gupta, Jenny van Dongen, Yu Fu, Abdel Abdellaoui, Rachel F. Tyndale, Vidya Velagapudi, Dorret I. Boomsma, Tellervo Korhonen, Jaakko Kaprio, Anu Loukola, Miina Ollikainen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Clinical Epigenetics
Subjects:
Epigenome-wide association study
Smoking
Cotinine
Genetic risk score
Nicotine metabolism
meQTL
Online Access:http://link.springer.com/article/10.1186/s13148-018-0606-9

Internet

http://link.springer.com/article/10.1186/s13148-018-0606-9

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