Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis

Jin et al use dynamic molecular network analysis to characterise the phosphoproteome in mouse models of neurodegenerative disease. Analyzing four models of frontotemporal lobar degeneration and four models of Alzheimer’s disease, they observe conserved signaling networks and confirm a therapeutic ef...

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Bibliographic Details
Main Authors: Meihua Jin, Xiaocen Jin, Hidenori Homma, Kyota Fujita, Hikari Tanaka, Shigeo Murayama, Hiroyasu Akatsu, Kazuhiko Tagawa, Hitoshi Okazawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02475-6