Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling

The Insulin signaling pathway couples growth, development and lifespan to nutritional conditions. Here, we demonstrate a function for the Drosophila lipoprotein LTP in conveying information about dietary lipid composition to the brain to regulate Insulin signaling. When yeast lipids are present in t...

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Bibliographic Details
Main Authors: Marko Brankatschk, Sebastian Dunst, Linda Nemetschke, Suzanne Eaton
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02862