The Role of HDACs as Leukemia Therapy Targets using HDI
Histone deacetylases (HDACs) are the enzymes causing deacetylation of histone and non-histone substrates. Histone deacetylase inhibitors (HDIs) are a family of drugs eliminating the effect of HDACs in malignant cells via inhibition of HDACs. Due to extensive effects upon gene expression through int...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2016-02-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
Subjects: | |
Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/367 |