The Role of HDACs as Leukemia Therapy Targets using HDI

The Role of HDACs as Leukemia Therapy Targets using HDI

Histone deacetylases (HDACs) are the enzymes causing deacetylation of histone and non-histone substrates. Histone deacetylase inhibitors (HDIs) are a family of drugs eliminating the effect of HDACs in malignant cells via inhibition of HDACs. Due to extensive effects upon gene expression through int...

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Bibliographic Details
Main Authors: Ahmad Ahmadzadeh, Elahe Khodadi, Mohammad Shahjahani, Jessika Bertacchini, Tina Vosoughi, Najmaldin Saki
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-02-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Histone deacetylases
Histone deacetylase inhibitors
leukemia
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/367

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/367

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