Importance of <i>NUDT15</i> Polymorphisms in Thiopurine Treatments

Thiopurines, mercaptopurine, and azathioprine are used as immunosuppressants in the treatments of inflammatory bowel disease, rheumatoid arthritis, and organ transplantation and as chemotherapeutic drugs for the treatment of acute leukemia and chronic myeloid leukemia. This drug class sometimes caus...

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Bibliographic Details
Main Authors: Yoichi Tanaka, Yoshiro Saito
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/11/8/778