β-Amyloid (β/A4) deposition in the medial temporal lobe in Down's syndrome: effects of brain region and patient age

The density of diffuse, primitive, classic and compact β-amyloid (β/A4) deposits was studied in the medial temporal lobe in 12 cases of Down's syndrome (DS) from 38 to 67 years of age. Total β/A4 deposit density was greater in the adjacent cortex compared with regions of the hippocampus, and th...

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Bibliographic Details
Main Authors: Richard A. Armstrong, Christopher U.M. Smith
Format: Article
Language:English
Published: Elsevier 1994-12-01
Series:Neurobiology of Disease
Subjects:
age
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996184700179