Myosin V executes steps of variable length via structurally constrained diffusion

The molecular motor myosin V transports cargo by stepping on actin filaments, executing a random diffusive search for actin binding sites at each step. A recent experiment suggests that the joint between the myosin lever arms may not rotate freely, as assumed in earlier studies, but instead has a pr...

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Bibliographic Details
Main Authors: David Hathcock, Riina Tehver, Michael Hinczewski, D Thirumalai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/51569