Use of magnoflorine-phospholipid complex to permeate blood-brain barrier and treat depression in the CUMS animal model

Use of magnoflorine-phospholipid complex to permeate blood-brain barrier and treat depression in the CUMS animal model

To improve the liposolubility and blood-brain barrier permeability of magnoflorine, a new formulation of magnoflorine-phospholipid complex was prepared, characterized, and pharmacologically evaluated in the chronic unpredictable mild stress animal model. In this paper, the magnoflorine-phospholipid...

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Bibliographic Details
Main Authors: Bingjie Li, Linmeng Han, Bingyan Cao, Xiaoying Yang, Xuehui Zhu, Bing Yang, Haodong Zhao, Wei Qiao
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
magnoflorine-phospholipid complex
physicochemical characterization
in vivo blood-brain distribution
pharmacological evaluation
western blotting analysis
Online Access:http://dx.doi.org/10.1080/10717544.2019.1616236

Internet

http://dx.doi.org/10.1080/10717544.2019.1616236

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