Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain

Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain

Neurons communicate by the activity-dependent release of small-molecule neurotransmitters packaged into synaptic vesicles (SVs). Although many molecules have been identified as neurotransmitters, technical limitations have precluded a full metabolomic analysis of SV content. Here, we present a workf...

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Bibliographic Details
Main Authors: Lynne Chantranupong, Jessica L Saulnier, Wengang Wang, Drew R Jones, Michael E Pacold, Bernardo L Sabatini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
synaptic vesicle
metabolomics
neurotransmitters
Online Access:https://elifesciences.org/articles/59699

Internet

https://elifesciences.org/articles/59699

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