Eosinophilia Associated With CD3−CD4+ T Cells: Characterization and Outcome of a Single-Center Cohort of 26 Patients

Eosinophilia Associated With CD3−CD4+ T Cells: Characterization and Outcome of a Single-Center Cohort of 26 Patients

Background: Lymphocytic variant hypereosinophilic syndrome is characterized by marked over-production of eosinophilopoietic factor(s) by dysregulated T cells leading to eosinophil expansion. In most cases, these T cells are clonal and express a CD3−CD4+ phenotype. As this is a rare disorder, present...

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Bibliographic Details
Main Authors: Caroline Carpentier, Sylvain Verbanck, Liliane Schandené, Pierre Heimann, Anne-Laure Trépant, Elie Cogan, Florence Roufosse
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
lymphocytic variant hypereosinophilic syndrome
CD3−CD4+ T cells
interleukin-5
TARC (CCL17)
fasciitis
interferon-alpha
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01765/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01765/full

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