Enhanced GIP Secretion in Obesity Is Associated with Biochemical Alteration and miRNA Contribution to the Development of Liver Steatosis

Enhanced GIP Secretion in Obesity Is Associated with Biochemical Alteration and miRNA Contribution to the Development of Liver Steatosis

Nutrient excess enhances glucose-dependent insulinotropic polypeptide (GIP) secretion, which may in turn contribute to the development of liver steatosis. We hypothesized that elevated GIP levels in obesity may affect markers of liver injury through microRNAs. The study involved 128 subjects (body m...

Full description

Bibliographic Details
Main Authors: Joanna Góralska, Urszula Raźny, Anna Polus, Agnieszka Dziewońska, Anna Gruca, Anna Zdzienicka, Aldona Dembińska-Kieć, Bogdan Solnica, Agnieszka Micek, Maria Kapusta, Krystyna Słowińska-Solnica, Małgorzata Malczewska-Malec
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Nutrients
Subjects:
gip
obesity
mirna
liver steatosis
fgf-21
fgf-19
cytokeratin-18
gut–liver cross-talk
Online Access:https://www.mdpi.com/2072-6643/12/2/476

Internet

https://www.mdpi.com/2072-6643/12/2/476

Similar Items