MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells

MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells

Abstract Background Cancer/testis antigens (CTAs) are a special type of tumor antigen and are believed to act as potential targets for cancer immunotherapy. Methods In this study, we first screened a rational CTA MAGE-A1 for lung adenocarcinoma (LUAD) and explored the detailed characteristics of MAG...

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Bibliographic Details
Main Authors: Yuan Mao, Weifei Fan, Hao Hu, Louqian Zhang, Jerod Michel, Yaqin Wu, Jun Wang, Lizhou Jia, Xiaojun Tang, Li Xu, Yan Chen, Jin Zhu, Zhenqing Feng, Lin Xu, Rong Yin, Qi Tang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Hematology & Oncology
Subjects:
Lung adenocarcinoma
Cancer/testis antigen
MAGE
CAR-T cell
Online Access:http://link.springer.com/article/10.1186/s13045-019-0793-7

Internet

http://link.springer.com/article/10.1186/s13045-019-0793-7

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