Anti-HIV-1 integrase activity of compounds from Cassia garrettiana heartwood

The ethanol extract of heartwood from Cassia garrettiana had strong anti-HIV-1 integrase (IN) activity with an IC50 value of 3.0 µg/mL. Therefore, its fractions and compounds were investigated for their anti-HIV-1 IN effect using the multiplate integration assay (MIA). From bioassay-guided isolation...

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Bibliographic Details
Main Authors: Kingkan Bunluepuech, Chatchai Wattanapiromsaku, Supinya Tewtrakul
Format: Article
Language:English
Published: Prince of Songkla University 2013-12-01
Series:Songklanakarin Journal of Science and Technology (SJST)
Subjects:
Online Access:http://rdo.psu.ac.th/sjstweb/journal/35-6/35-6-7.pdf