Rapamycin Alleviates the Symptoms of Multiple Sclerosis in Experimental Autoimmune Encephalomyelitis (EAE) Through Mediating the TAM-TLRs-SOCS Pathway

Rapamycin Alleviates the Symptoms of Multiple Sclerosis in Experimental Autoimmune Encephalomyelitis (EAE) Through Mediating the TAM-TLRs-SOCS Pathway

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Our research aimed to find an immunomodulatory therapy for MS. An experimental autoimmune encephalomyelitis (EAE) mouse model of MS was established induced with the syntheticmyelin oligodendrocyte g...

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Bibliographic Details
Main Authors: Xiao-ling Li, Bo Zhang, Wei Liu, Meng-jiao Sun, Ya-lan Zhang, Hui Liu, Man-xia Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
rapamycin
GAS6
TAM
TAM-TLRs-SOCS pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.590884/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.590884/full

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