GPR120 is an important inflammatory regulator in the development of osteoarthritis

GPR120 is an important inflammatory regulator in the development of osteoarthritis

Abstract Background The aim of this study was to investigate the regulatory role of G-protein coupled receptor 120 (GPR120) in the development and progression of osteoarthritis (OA). Methods GPR120 knockout (KO) and wild-type (WT) mice were used to create an animal model of OA by means of anterior c...

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Bibliographic Details
Main Authors: Yuanfeng Chen, Dan Zhang, Ki Wai Ho, Sien Lin, Wade Chun-Wai Suen, Huantian Zhang, Zhengang Zha, Gang Li, Po Sing Leung
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Arthritis Research & Therapy
Subjects:
G-protein coupled receptors
Polyunsaturated fatty acids
Proinflammatory mediators
Cartilage
Subchondral bone
Skin defect
Online Access:http://link.springer.com/article/10.1186/s13075-018-1660-6

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http://link.springer.com/article/10.1186/s13075-018-1660-6

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