Deciphering the Binding Interactions between <i>Acinetobacter baumannii</i> ACP and β-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy

Deciphering the Binding Interactions between <i>Acinetobacter baumannii</i> ACP and β-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy

Fatty acid synthesis is essential for bacterial viability. Thus, fatty acid synthases (FASs) represent effective targets for antibiotics. Nevertheless, multidrug-resistant bacteria, including the human opportunistic bacteria, <i>Acinetobacter baumannii,</i> are emerging threats. Meanwhil...

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Bibliographic Details
Main Authors: Sungjae Choi, Jungwoo Park, Jiwon Yeon, Ahjin Jang, Woo Cheol Lee, Yangmee Kim
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>A. baumannii</i>
fatty acid synthesis
acyl carrier protein
KAS III
protein–protein interaction (PPI) inhibitor
NMR spectroscopy
Online Access:https://www.mdpi.com/1422-0067/22/7/3317

Internet

https://www.mdpi.com/1422-0067/22/7/3317

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