Inhibition of nuclear factor (erythroid-derived 2)-like 2 promotes hepatic progenitor cell activation and differentiation

Inhibition of nuclear factor (erythroid-derived 2)-like 2 promotes hepatic progenitor cell activation and differentiation

Abstract The stem cell ability to self-renew and lead regeneration relies on the balance of complex signals in their microenvironment. The identification of modulators of hepatic progenitor cell (HPC) activation is determinant for liver regeneration and may improve cell transplantation for end-stage...

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Main Authors: Francesco Bellanti, Giorgia di Bello, Giuseppina Iannelli, Giuseppe Pannone, Maria Carmela Pedicillo, Luke Boulter, Wei-Yu Lu, Rosanna Tamborra, Rosanna Villani, Gianluigi Vendemiale, Stuart J. Forbes, Gaetano Serviddio
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00137-z

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https://doi.org/10.1038/s41536-021-00137-z

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