Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

Capsular polysaccharides are important factors in bacterial pathogenesis and have been the target of a number of successful vaccines. Francisella tularensis has been considered to express a capsular antigen but none has been isolated or characterized. We have developed a monoclonal antibody, 11B7, w...

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Bibliographic Details
Main Authors: Michael A Apicella, Deborah M B Post, Andrew C Fowler, Bradley D Jones, Jed A Rasmussen, Jason R Hunt, Sayaka Imagawa, Biswa Choudhury, Thomas J Inzana, Tamara M Maier, Dara W Frank, Thomas C Zahrt, Kathryn Chaloner, Michael P Jennings, Molly K McLendon, Bradford W Gibson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2897883?pdf=render

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http://europepmc.org/articles/PMC2897883?pdf=render

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