The significant role of redox system in myeloid leukemia: from pathogenesis to therapeutic applications

The significant role of redox system in myeloid leukemia: from pathogenesis to therapeutic applications

Abstract Background Excessive generation of reactive oxygen species (ROS) in the presence of a defective antioxidant system can induce cellular damage and disrupt normal physiological functions. Several studies have revealed the unfavorable role of ROS in promoting the growth, proliferation, migrati...

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Bibliographic Details
Main Authors: Natasha Mupeta Kaweme, Shu Zhou, Geoffrey Joseph Changwe, Fuling Zhou
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Biomarker Research
Subjects:
Acute myeloid leukemia
Reactive oxygen species
Oxidative stress
Oncogene mutations
Jab1/COPS5
Antioxidants
Online Access:http://link.springer.com/article/10.1186/s40364-020-00242-z

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http://link.springer.com/article/10.1186/s40364-020-00242-z

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