Application of a Biphasic Mathematical Model of Cancer Cell Drug Response for Formulating Potent and Synergistic Targeted Drug Combinations to Triple Negative Breast Cancer Cells

Triple negative breast cancer is a collection of heterogeneous breast cancers that are immunohistochemically negative for estrogen receptor, progesterone receptor, and ErbB2 (due to deletion or lack of amplification). No dominant proliferative driver has been identified for this type of cancer, and...

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Bibliographic Details
Main Authors: Jinyan Shen, Li Li, Niall G. Howlett, Paul S. Cohen, Gongqin Sun
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/5/1087