Case report: a thiazide diuretic to treat polyuria induced by tolvaptan

Abstract Background Currently, the vasopressin V2 receptor antagonist tolvaptan is the only available treatment for autosomal dominant polycystic kidney disease (ADPKD), but there are tolerability issues due to aquaretic side-effects such as polyuria. A possible strategy to ameliorate these side-eff...

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Bibliographic Details
Main Authors: Bart J. Kramers, Maatje D. A. van Gastel, Esther Meijer, Ron T. Gansevoort
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-018-0957-7