A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

Abstract Background The understanding of changes in temporal processes related to human carcinogenesis is limited. One approach for prospective functional genomic studies is to compile trajectories of differential expression of genes, based on measurements from many case-control pairs. We propose a...

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Bibliographic Details
Main Authors: Eiliv Lund, Lars Holden, Hege Bøvelstad, Sandra Plancade, Nicolle Mode, Clara-Cecilie Günther, Gregory Nuel, Jean-Christophe Thalabard, Marit Holden
Format: Article
Language:English
Published: BMC 2016-03-01
Series:BMC Medical Research Methodology
Subjects:
Transcriptomics
Gene expression
NOWAC postgenome cohort
Breast cancer
Carcinogenesis
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12874-016-0129-z

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http://link.springer.com/article/10.1186/s12874-016-0129-z

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