Abilities of candesartan and other AT receptor blockers to impair angiotensin II-induced AT receptor activation after wash-out
Angiotensin II (Ang II) binds to Ang II type 1 (AT 1 ) receptor and evokes cell signaling, and subsequently stimulates vasoconstriction and cell proliferation, which eventually lead to cardiovascular disease. Since most AT 1 receptor blockers (ARBs) have molecular (differential) effects, we evaluate...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi - SAGE Publishing
2012-03-01
|
| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.1177/1470320311417478 |