Blood Interferon-α Levels and Severity, Outcomes, and Inflammatory Profiles in Hospitalized COVID-19 Patients

Blood Interferon-α Levels and Severity, Outcomes, and Inflammatory Profiles in Hospitalized COVID-19 Patients

Background: Deficient interferon responses have been proposed as one of the relevant mechanisms prompting severe manifestations of COVID-19.Objective: To evaluate the interferon (IFN)-α levels in a cohort of COVID-19 patients in relation to severity, evolution of the clinical manifestations and immu...

Full description

Bibliographic Details
Main Authors: Marco Contoli, Alberto Papi, Luca Tomassetti, Paola Rizzo, Francesco Vieceli Dalla Sega, Francesca Fortini, Francesca Torsani, Luca Morandi, Luca Ronzoni, Ottavio Zucchetti, Rita Pavasini, Alberto Fogagnolo, Carlo Alberto Volta, Nathan W. Bartlett, Sebastian L. Johnston, Savino Spadaro, Gianluca Campo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
interferon
SARS–CoV−2
COVID−19
respiratory failure
mortality
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.648004/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.648004/full

Similar Items