GluN2D NMDA Receptors Gate Fear Extinction Learning and Interneuron Plasticity

GluN2D NMDA Receptors Gate Fear Extinction Learning and Interneuron Plasticity

The cerebellum is critically involved in the formation of associative fear memory and in subsequent extinction learning. Fear conditioning is associated with a long-term potentiation at both excitatory and inhibitory synapses onto Purkinje cells. We therefore tested whether fear conditioning unmasks...

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Bibliographic Details
Main Authors: Christophe J. Dubois, Siqiong June Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
GluN2D NMDA receptor
fear conditioning
extinction learning
metaplasticity
long-term depression
inhibitory synapses
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.681068/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2021.681068/full

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