Glycans in sera of amyotrophic lateral sclerosis patients and their role in killing neuronal cells.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by degeneration of upper and lower motor neurons. To date, glycosylation patterns of glycoproteins in fluids of ALS patients have not been described. Moreover, the aberrant glycosylation related to the pathogenesis of ot...

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Bibliographic Details
Main Authors: Meital Edri-Brami, Benyamin Rosental, Dana Hayoun, Michael Welt, Hila Rosen, Itzhak Wirguin, Beatrice Nefussy, Vivian E Drory, Angel Porgador, Rachel G Lichtenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364259?pdf=render