Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development

More than 85% of advanced breast cancer patients suffer from metastatic bone lesions, yet the mechanisms that facilitate these metastases remain poorly understood. Recent studies suggest that tumor-derived factors initiate changes within the tumor microenvironment to facilitate metastasis. However,...

Full description

Bibliographic Details
Main Authors: Xianmin Luo, Yujie Fu, Andrew J. Loza, Bhavna Murali, Kathleen M. Leahy, Megan K. Ruhland, Margery Gang, Xinming Su, Ali Zamani, Yu Shi, Kory J. Lavine, David M. Ornitz, Katherine N. Weilbaecher, Fanxin Long, Deborah V. Novack, Roberta Faccio, Gregory D. Longmore, Sheila A. Stewart
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014291

Internet

http://www.sciencedirect.com/science/article/pii/S2211124715014291

Similar Items