Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies

Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies

Danggui Buxue Tang (DBT), an ancient Chinese herbal decoction commonly used to mitigate menopausal osteoporosis, contains two herbs: Astragali Radix (AR) and Angelicae Sinensis Radix (ASR). The exact efficacy of individual chemical(s) within DBT, or in any herbal mixture, is hard to be revealed. Cal...

Full description

Bibliographic Details
Main Authors: Amy G. W. Gong, Ran Duan, Huai Y. Wang, Tina T. X. Dong, Karl W. K. Tsim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
Astragali Radix
Angelicae Sinensis Radix
Danggui Buxue Tang
RNA-seq
metabolomics
osteoblast
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00036/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00036/full

Similar Items