Calcium dysregulation in atrial fibrillation: the role of CaMKII

Atrial fibrillation (AF) is the most frequently encountered clinical arrhythmia and is associated with increased morbidity and mortality. Ectopic activity and reentry are considered major arrhythmogenic mechanisms contributing to the initiation and maintenance of AF. In addition, AF is self-reinforc...

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Bibliographic Details
Main Authors: Jordi eHeijman, Niels eVoigt, Xander H T Wehrens, Dobromir eDobrev
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00030/full