Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy.

Radiofrequency thermal ablation (RFA) of hepatic and renal tumors can be accompanied by non-desired tumorigenesis in residual, untreated tumor. Here, we studied the use of micelle-encapsulated siRNA to suppress IL-6-mediated local and systemic secondary effects of RFA.We compared standardized hepati...

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Bibliographic Details
Main Authors: Muneeb Ahmed, Gaurav Kumar, Gemma Navarro, Yuanguo Wang, Svetlana Gourevitch, Marwan H Moussa, Nir Rozenblum, Tatyana Levchenko, Eithan Galun, Vladimir P Torchilin, S Nahum Goldberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4495977?pdf=render