Antibody-mediated rejection of arterialised venous allografts is inhibited by immunosuppression in rats.

OBJECTIVES AND DESIGN: We determined in a rat model (1) the presence and dynamics of alloantibodies recognizing MHC complexes on quiescent Brown-Norway (BN) splenic cells in the sera of Lewis (LEW) recipients of Brown-Norway iliolumbar vein grafts under tacrolimus immunosuppression; and (2) the pres...

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Main Authors: Katrin Splith, Peter Fellmer, Ivan Matia, Martin Varga, Martin Oliverius, Stephanie Kuhn, Linda Feldbrügge, Felix Krenzien, Hans-Michael Hau, Georg Wiltberger, Moritz Schmelzle, Sven Jonas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3949981?pdf=render