Sex differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males.

<h4>Background</h4>Susceptibility to viral infections as well as their severity are higher in men than in women. Heightened antiviral responses typical of women are effective for rapid virus clearance, but if excessively high or prolonged, can result in chronic/inflammatory pathologies....

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Main Authors: Maria Gabriella Torcia, Lucia Nencioni, Ann Maria Clemente, Livia Civitelli, Ignacio Celestino, Dolores Limongi, Giulia Fadigati, Eloisa Perissi, Federico Cozzolino, Enrico Garaci, Anna Teresa Palamara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22768144/?tool=EBI