Multiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing.

Multiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing.

Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the mitochondrial genome has a unique structural organization consisting of 20-50 maxicircles (∼20 kb) and thousands of minicircles (0.5-10 kb)....

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Bibliographic Details
Main Authors: Louisa A Messenger, Martin S Llewellyn, Tapan Bhattacharyya, Oscar Franzén, Michael D Lewis, Juan David Ramírez, Hernan J Carrasco, Björn Andersson, Michael A Miles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3323513?pdf=render

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http://europepmc.org/articles/PMC3323513?pdf=render

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