Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity
A series of <i>Bis</i>-pyrazole Schiff bases (<b>6a</b>–<b>d</b> and <b>7a</b>–<b>d</b>) and mono-pyrazole Schiff bases (<b>8a</b>–<b>d</b> and <b>9a</b>–<b>d</b>) were designed and synthesize...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/11/2593 |