Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival
Breast cancer heterogeneity in histology and molecular subtype influences metabolic and proliferative activity and hence the acid load on cancer cells. We hypothesized that acid-base transporters and intracellular pH (pHi) dynamics contribute inter-individual variability in breast cancer aggressiven...
Main Authors: | Nicolai J Toft, Trine V Axelsen, Helene L Pedersen, Marco Mele, Mark Burton, Eva Balling, Tonje Johansen, Mads Thomassen, Peer M Christiansen, Ebbe Boedtkjer |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/68447 |
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