Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.

Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.

Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni is the most common. Pharmacological treatment is limited to the use of a single drug, praziquantel (P...

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Main Authors: Maria A Guimarães, Rosimeire N de Oliveira, Rebeca L de Almeida, Ana C Mafud, Ana L V Sarkis, Rayane Ganassin, Marcos P da Silva, Daniel B Roquini, Leiz M Veras, Tânia C H Sawada, Cristina D Ropke, Luis A Muehlmann, Graziella A Joanitti, Selma A S Kuckelhaus, Silmara M Allegretti, Yvonne P Mascarenhas, Josué de Moraes, José R S A Leite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5947907?pdf=render

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http://europepmc.org/articles/PMC5947907?pdf=render

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