The first case of primary hypertrophic osteoarthropathy with soft tissue giant tumors caused by HPGD loss-of-function mutation

The first case of primary hypertrophic osteoarthropathy with soft tissue giant tumors caused by HPGD loss-of-function mutation

Background: Primary hypertrophic osteoarthropathy (PHO) is a rare genetic multi-organic disease characterized by digital clubbing, periostosis and pachydermia. Two genes, HPGD and SLCO2A1, which encodes 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and prostaglandin transporter (PGT), respectively...

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Bibliographic Details
Main Authors: Qianqian Pang, Yuping Xu, Xuan Qi, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Ling Qin, Weibo Xia
Format: Article
Language:English
Published: Bioscientifica 2019-06-01
Series:Endocrine Connections
Subjects:
primary hypertrophic osteoarthropathy
PHO
HPGD mutation
soft tumor
COX2 selective inhibitor treatment
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/6/EC-19-0149.xml

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https://ec.bioscientifica.com/view/journals/ec/8/6/EC-19-0149.xml

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