Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor

Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor

Abstract Background Functional compartmentalization has emerged as an important factor modulating the kinetics and specificity of biochemical reactions in the nucleus, including those involved in transcriptional regulation. The glucocorticoid receptor (GR) is a ligand-activated transcription factor...

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Bibliographic Details
Main Authors: Martin Stortz, Adali Pecci, Diego M. Presman, Valeria Levi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Biology
Subjects:
Glucocorticoid receptor
Membraneless organelles
Phase separation
Biomolecular condensates
Live-cell imaging
Transcription factor
Online Access:http://link.springer.com/article/10.1186/s12915-020-00788-2

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http://link.springer.com/article/10.1186/s12915-020-00788-2

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