Multiplex HPV RNA in situ hybridization/p16 immunohistochemistry: a novel approach to detect papillomavirus in HPV-related cancers. A novel multiplex ISH/IHC assay to detect HPV

Abstract Background High-risk human papillomavirus (HR-HPV) is notoriously associated with tumor progression in a broad spectrum of malignancies. Detection of HR-HPV is clinically important in the management of HPV-related carcinomas, particularly in cervical cancer and oropharyngeal squamous cell c...

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Bibliographic Details
Main Authors: Federica Zito Marino, Andrea Ronchi, Marianna Stilo, Immacolata Cozzolino, Elvira La Mantia, Nicola Colacurci, Giuseppe Colella, Renato Franco
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Infectious Agents and Cancer
Subjects:
ISH
HPV
p16
Online Access:http://link.springer.com/article/10.1186/s13027-020-00310-x