The Merkel Cell Polyomavirus T Antigens Function as Tumor Promoters in Murine Skin

Merkel cell polyomavirus (MCPyV) causes the majority of human Merkel cell carcinomas (MCC), a rare but highly aggressive form of skin cancer. We recently reported that constitutive expression of MCC tumor-derived MCPyV tumor (T) antigens in the skin of transgenic mice leads to hyperplasia, increased...

Full description

Bibliographic Details
Main Authors: Megan E. Spurgeon, Amy Liem, Darya Buehler, Jingwei Cheng, James A. DeCaprio, Paul F. Lambert
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/2/222