Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

Adipose triglyceride lipase (ATGL) and comparative gene identification 58 (CGI-58) are critical regulators of triacylglycerol (TAG) turnover. CGI-58 is thought to regulate TAG mobilization by stimulating the enzymatic activity of ATGL. However, it is not known whether this coactivation function of C...

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Bibliographic Details
Main Authors: Caleb C. Lord, Daniel Ferguson, Gwynneth Thomas, Amanda L. Brown, Rebecca C. Schugar, Amy Burrows, Anthony D. Gromovsky, Jenna Betters, Chase Neumann, Jessica Sacks, Stephanie Marshall, Russell Watts, Martina Schweiger, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Justin D. Lathia, Takuya F. Sakaguchi, Richard Lehner, Guenter Haemmerle, Rudolf Zechner, J. Mark Brown
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cell Reports
Subjects:
triacylglycerol
lipase
neutral lipid storage disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716308038

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http://www.sciencedirect.com/science/article/pii/S2211124716308038

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