Combinatorial Engineering of Yarrowia lipolytica as a Promising Cell Biorefinery Platform for the de novo Production of Multi-Purpose Long Chain Dicarboxylic Acids

Combinatorial Engineering of Yarrowia lipolytica as a Promising Cell Biorefinery Platform for the de novo Production of Multi-Purpose Long Chain Dicarboxylic Acids

This proof-of-concept study establishes Yarrowia lipolytica (Y. lipolytica) as a whole cell factory for the de novo production of long chain dicarboxylic acid (LCDCA-16 and 18) using glycerol as the sole source of carbon. Modification of the fatty acid metabolism pathway enabled creating a pool of f...

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Bibliographic Details
Main Authors: Ali Abghari, Catherine Madzak, Shulin Chen
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Fermentation
Subjects:
Yarrowia lipolytica
long chain dicarboxylic acid
building blocks
citric acid
glycerol
genetic and metabolic engineering
fermentation
bioconversion
Online Access:https://www.mdpi.com/2311-5637/3/3/40

Internet

https://www.mdpi.com/2311-5637/3/3/40

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