Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women

Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women

Globally, bacterial vaginosis (BV) is a common condition in women. BV is associated with poorer reproductive health outcomes and HIV risk. Typically, BV represents a shift in the vaginal microbiome from one that is dominated by Lactobacillus to one that is diverse. Despite many women having similar...

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Bibliographic Details
Main Authors: Supriya D. Mehta, Drew R. Nannini, Fredrick Otieno, Stefan J. Green, Walter Agingu, Alan Landay, Yinan Zheng, Lifang Hou
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mSystems
Subjects:
vaginal microbiome
vaginal microbiota
bacterial vaginosis
gardnerella vaginalis
lactobacillus crispatus
lactobacillus iners
l. crispatus
l. iners
g. vaginalis
shannon diversity index
community state type
genome wide association study
pathway analysis
toll-like receptors
innate immune response
kenya
gwas
Online Access:https://doi.org/10.1128/mSystems.00502-20

Internet

https://doi.org/10.1128/mSystems.00502-20

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